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2021 NFL DFS Week 6 DraftKings Picks

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Welcome to the 2021 NFL DFS Week 6 DraftKings Picks!

Football truly is the greatest sport in the world. The adversity teams face. The dynasties that are built and crumble down overnight. The drama and turmoil, it’s like a soap opera for men. You’ve got to love it.

Each week it feels like there’s something new in the NFL for us to uncover.

Is the Kansas City Chiefs Dynasty crumbling?

The Jon Gruden fallout.

What to do to replace injured studs like Saquon Barkley or Clyde Edwards-Helaire?

So many questions and so many storylines!

That’s why we love this sport and love this league. Okay, enough of the preamble. Let’s dive into some Week 6 Draftkings picks that I break down weekly from a cash games perspective to help you win your 50/50’s and H2H’s!

2021 NFL DFS Week 6 DraftKings Picks

Click here for Wisdom of the Crowd NFL DFS projection

Quarterbacks

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Joe Burrow, Bengals @ Lions, $6,300

I’m drawing a lot of interest to Burrow this week. I was on him last week in tournaments but unfortunately, it wasn’t a great outcome, but I’m back to the well with Burrow again this week. The matchup has me drawing interest to him heavily.

The Lions are a layup in DFS, they rank 23rd in the NFL against QB’s in fantasy this season using Draftkings scoring format. So far this season they have yet to be able to hold any team to under 325 total yards of offense. Take a look at how QB’s performed versus the Lions this season.

It may not look impressive, but good QB’s like Rodgers tore the Lions up in the secondary. Yardage-wise, they can’t stop a high school varsity team against the passing offense.

The Lions are also allowing teams to score on them at a very high rate. They currently rank 25th in the NFL in points allowed per game at 27.6 allowed. Just terrible.

To make matters worse, Pro Football Focus has the matchup ratings for each of the three WR’s in the 75th percentile in terms of matchup advantage. Ja’Marr Chase is slotted in to have a 97% edge in his matchup, 2nd best in the NFL Sunday.

Tyler Boyd in the slot holds an 89.6% advantage while outside WR Tee Higgins is slotted in to have a 77.3% advantage. No matter how you slice it, the Bengals simply have too many dynamic receivers for the Lions to stack up with.

With the matchup being so elite we can’t forget the fact that Joe Burrow is just a flat-out baller. In every game this season, the second-year QB has thrown at least two touchdown passes leading to 12 points alone based on that metric.

Pair the multi-touchdown performance with his 257.8 yards per game and bam, an elite floor. So far on the season, Burrow has averaged 19.2 Draftkings points against much harder opponents. Now, the Bengals and their QB get to play a much easier task.

At his price point, I can’t get enough of Burrow who offers you elite 26 point upside and a nice floor of 19 points.

Taylor Heinicke, Washington vs Chiefs, $5,800

Listen, hear me out, you can’t get much better of a spot than this one for Heinicke and company. So far this season, the Chiefs have been one of if not the worst defense in the NFL. They rank last in DVOA per Football Outsiders and can’t stop a high school team on offense.

What makes things more interesting is the fact that the Washington Football Team’s defense is almost just as bad as the Chiefs’ defense. Take a look at this tweet that sums everything up perfectly.

It speaks for itself, both teams are just plain garbage on defense. Heinicke should be able to take full advantage of this defense. They don’t have a soul that can cover superstar Terry McLaurin on the outside or in the slot.

Moving past the matchup which is the 6th best on the slate, the baseline for success has been there in fantasy this season for the veteran QB. In four games of relief work for Ryan Fitzpatrick, here’s how Heinicke has scored in terms of DraftKings points.

  • 24.04 points
  • 23.38 points
  • 27.90 points
  • 11.92 points

You can see just how successful he can be when put in the right spot. All those 20+ point performances came against the following teams, Falcons, Bills, and Giants. One of those is subsequently an elite defense, but the other two are just as garbage as the Chiefs.

According to PFF, the Football Team hold the highest pass blocking advantage on the slate as well at 42% over the Chiefs pass rush. They also hold a 45% edge in the run game as well which ranks 6th. No matter how you slice it, it’s easy pickings for Heinicke and company.

At this price point, he unlocks the ability to get you high-priced studs to jam into your lineup like a Davante Adams. The matchup is perfect and so is the salary.

Running Backs

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Jonathan Taylor, Colts vs Texans, $6,600

Coming off a first-round pick in Fantasy, managers have been shaky on Taylor so far to start the seasons as well as DraftKings players. As of late, Taylor has been kicking it up and scoring tons of points for managers alike.

On Monday against the Ravens, Taylor topped 34.9 Draftkings points against a decent Ravens rushing defense. Last week, Taylor also racked up 23.4 Draftkings points. Two very nice bounce-back weeks after what was a disappointing start to the season as he failed to top over 10 points the previous two weeks.

Now, the situation for Taylor and the Colts brightens coming off a disappointing ending to Monday night football. The Colts get to square off against division rivals, Houston Texans, one of the league’s worst teams in the NFL. The Texans matchup up very nicely for Taylor to have a great day.

They currently rank 31st in the NFL against RB’s allowing 134.8 yards per game, 7th most in the NFL. Indianapolis also holds a very nice run blocking advantage over the porous Texans’ run defense. According to PFF, the Colts hold a 39% blocking advantage, the 10th highest on the slate.

The volume also sets up quite nicely for a Taylor bounceback as well. In all five games this season, Taylor has seen over 10 carries, and in 4-of-5 games, he’s logged 15 or more carries. The rushing floor is tremendous for the second-year standout. In recent weeks, he’s also seen nice passing volume.

The past two weeks combined, the tailback has seen seven targets as Nyheim Hines remains banged up and likely will be on Sunday as well. Passing game usage mixed in with such high rushing floor in a potential blowout where the Colts may lead wire to wire, Taylor could smash.

His cheap price point for what could be a 20 point or more running back is a great value compared to someone like Nick Chubb or Antonio Gibson who are similar or even higher priced.

Darrell Henderson, Rams @ Giants, $6,000

The floor is the ceiling for Henderson, in the first four weeks in the season there may not be a more consistent back than Henderson. In each of the first four games he’s played, the veteran has grabbed 15.7 or more DraftKings points in each. He hasn’t flashed the upside but the floor is amazing with him.

Why not play the floor in cash games though? So far he’s scored 15.7 against the Bears, 17.2 against the Colts, 16.6 against the Colts, and 16.9 points against the Seahawks last week. Ideal for a guy who is taking nearly 100% of the snaps when healthy.



Also, it’s great to see that Henderson is getting plenty of volume in the running and passing game. The third-year back has seen 13 or more carries in every game alongside 13 targets through four games as well. You have to love the volume for a guy in a high-powered offense.

However, the most exciting part hasn’t even been touched on yet, the fact the Rams play the Giants as what will likely be 10-13 point spread favorites. Do you know what that means? When the games are in blowout situations, Henderson will do a whole bunch of running to ice the game.

But it’s not just the fact that they are heavy favorites, it’s just how bad the Giants have been against the run. According to Team Rankings, the Giants are allowing the 6th most rushing yards per game as well as the 19th most points per game to the position on Draftkings.

Now, the high-flying rams come to town as huge favorites versus a lifeless team with one win that just lost its starting QB to a concussion, not great. I’m all in on Henderson at this cheap price point.

Khalil Herbert, Bears vs Packers, $4,600

I just want to start by saying this will be the chalk this weekend. But guess what, it doesn’t matter. Cash games you can eat the chalk, we saw it last week with guys like Derrick Henry and Ricky Seals-Jones. This week is more of the same with Herbert.

Week 5 gave us our first taste of the rookie sixth-round pick, the young man ran the ball 18 times for 75 yards, that’s a modest 4.2 yards per carry. A note that won’t show up during the box score is the fact that Herbert ran a route on 22% of the team’s dropbacks despite not seeing passing work.

Don’t let the fact that he is a sixth-round pick or the team’s third back fool you, this kid is talented. Take a look at these clips below.

Do we have a star in the making? Maybe so. All I know is that the Packers are garbage against the run. They are allowing 100+ yards a game to the position and currently have a -24% advantage versus the Bears offensive line. Easy.

Don’t always look at the numbers on the surface, the Packers are allowing 25.1 points to the RB position so far on the season, and honestly, I’m surprised it’s not more. This team when you use the eye test has just been terrible.

I love Herbert as the only RB on the team Sunday with Damien Williams out with COVID-19. He should see plenty of usage in both the passing game and running game.

Wide Receivers

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Tyreek Hill, Chiefs @ Washington, $8,500

Who can give you 50 points on this slate? The answer is nobody outside of Tyreek. In Week 1 and 4, Hill scored 40 and 50 Draftkings points. Now, a pissed-off Chiefs team with Hill as the leaders heads to Washington to try and hang onto playoff hopes.

After getting dominated by the Bills on Monday night, the Chiefs are going to be very angry. It’s not going to be fun to be on the Washington Football Team this Sunday. Hill and Mahomes might go nuclear.

In an earlier tweet, you saw someone mention just how bad both teams are. Each team is allowing 295 yards or more in every single game. That’s a recipe for success for Hill and company.

One thing that Hill gives you is the touchdown upside and the fact that he sees tons of volume. In three of his five games, he’s seen 10+ targets. Hill also has seen four touchdowns this season as well.

There isn’t much to say about Hill. He’s a high-priced stud on a pissed-off Chiefs team that is fighting for its life Sunday. Play him.

Jakobi Meyers, Patriots vs Cowboys, $5,500

I’m going back to the well with this one. I’ve preached about Meyers all over Twitter as of late. Last Sunday, we saw the Patriots look very shaky in the first half but mount a 14-point comeback against the Texans. The offense was stagnant but lead by Mac Jones and Meyers came back.

Now, with Damien Harris limited and potentially going to miss, the Patriots are going to have to scrap the run game and pass much more often. Take a look at my tweet below.

Meyers is in a buy-low bounce-back spot against one of the worst secondaries in the NFL. The Cowboys allow the 20th most points per game to the WR position but are getting torched to the tune of 311 yards a game, 31st in the NFL. They are just a miserable secondary outside of Diggs.

In comes Meyers and a Patriots in a bounce-back spot. The full-PPR scoring boosts Meyers with his clear target share and catch ratio. In a great spot at a cheap mid-tier price point, I’m playing Meyers.

Tee Higgins, Bengals @ Lions, $5,300

Take a look above, I touched on Joe Burrow and how much I love him in this spot. Stacking the two together would be a prime time example of great correlation which is super important in DFS.

Higgins currently bolsters a 77.3% matchup advantage versus a week secondary in Detroit, it ranks within the top-15 at his position.

The connection that both Burrow and Higgins share is a fascinating one. The pair showed great chemistry in their first years together and have continued it into year two. In three games healthy this season, the standout WR has seen five, 10, and seven targets.

Great numbers to say the least, with those targets he has also produced a top-five red zone target percentage in the NFL. What has he done with those red zone targets? Well, he’s scored two touchdowns in only three games. 66.7%, we take those every day of the week.

With a nice team total, great environment, an array of targets, and a cupcake matchup, I’m getting tons of Higgins in my cash games lineups due to his safety and upside.

Honorable Mention: Amon-Ra St. Brown, $4,200

Tight Ends

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Ricky Seals-Jones, Washington vs Chiefs, $3,000

Who? Ricky Seals-Jones is who, Logan Thomas‘ replacement after he went on injured reserve. In the first game without Thomas, Seals-Jones absolutely balled out he caught 5-of-8 balls, for 41 yards. Very solid, but it’s not exactly what meets the eye.

Seals-Jones logged 99% of the snaps, more than any other TE in the NFL on Sunday including Kelce and Waller. Just being on the field may not sound like much but that means more routes and targets at the end of the day. With the attention likely pointing towards Terry McLaurin, Seals-Jones may find himself on underneath routes.

This 24th ranked defense against the TE will have their hands full. In such an easy matchup and considering the $3,000 price points, he is squarely in play to help you get up to some high-priced studs.

Honorable Mentions: Dalton Schultz, $4,900


Wisdom of the Crowd NFL DFS projections


Click here to read Jesse’s Week 6 FanDuel Picks

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